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Title: Conventional and novel approaches for colon specific drug delivery
Alternative title / Subtitle: a review
Authors: Kothawade, P. D.
Gangurde, H. H.
Surawase, R. K.
Wagh, M. A.
Tamizharasi, S.
Item type: Conference publication
Keywords: Azo hydrogels;Αζω υδρογέλη;Colon specific drug delivery;Pressure-controlled colon delivery capsules;CODES"
Subjects: Medicine
Issue Date: 2-Feb-2015
Date of availability: 2-Feb-2015
Publisher: Νερατζής, Ηλίας
Σιανούδης, Ιωάννης
Abstract: Lot of research is undergoing in colon specific drug delivery as this drug delivery route is not only useful for targeting the drugs required in the treatment of diseases associated with colon, but also as a potential site for the local and systemic delivery of peptide and proteins and other therapeutic drugs. Precise colon drug delivery requires the triggering mechanism in the delivery system that can respond only to the physiological conditions specific to the colon. The primary conventional approaches used to obtain colon-specific delivery were based on prodrugs, pH and timedependent systems or microflora activated systems and achieved limited success. However, recently continuous efforts have been taken on designing colon-specific delivery systems with improved site specificity and versatile drug release kinetics to accomplish different therapeutic needs. The focus of this review is to provide detailed insight into the conventional as well as recent approaches used to target the therapeutic agents specifically to the colon.
Description: Running Title: Approaches for Colon specific drug delivery.
Language: English
Citation: Kothawade, P. D., Gangurde, H. H., Surawase, R. K., Wagh, M. A. & Tamizharasi, S. (2011) Conventional and novel approaches for colon specific drug delivery: a review. "e-Journal of Science & Technology". [Online] 6 (4). p. 33-56. Available from: [Accessed 2-02-2015]
Journal: e-Περιοδικό Επιστήμης & Τεχνολογίας
e-Journal of Science & Technology
Type of Journal: With a review process (peer review)
Access scheme: Publicly accessible
License: Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες
Appears in Collections:Τόμος 06, τεύχος 4 (2011)

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