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Title: Thrombolytic and anti-arthritic activities of methanolic extract of trevesia palmata
Authors: Mohammed, Aktar Sayeed
Faruk, Md.
Chowdhury, Ahmad Ibtehaz
Faisal, Ahmmed Rusti
Al Mamun, Abdullah
Contributors: Mujahidul, Islam
Item type: Conference publication
Keywords: Trevesia palmata;Thrombolytic;Anti arthritic;Clot lysis;Inhibition;Protein denaturation;Θρομβολυτική;Αντί αρθριτικός;Λύση θρόμβου;Αναστολή;Μετουσίωση πρωτεΐνης
Subjects: Medicine
Issue Date: 17-Feb-2015
Date of availability: 17-Feb-2015
Publisher: Νερατζής, Ηλίας
Σιανούδης, Ιωάννης
Abstract: The crude methanol extract of the leaves of Trevesia palmata was partitioned with nhexane, ethyl acetate, chloroform and water for biological investigation. Methanol extract of Trevesia palmata was assessed for in vitro thrombolytic and anti-arthritic activity. Anti- arthritic activity was evaluated using albumin denaturation. Diclofenac sodium (D.s.) was used as a standard drug for the study of anti-inflammatory activity. The methanol extract of Trevesia palmata showed mean inhibition of protein denaturation 89.24±0.6584 at 1000µg/ml whereas, standard diclofenac sodium it was found to be 96.77±1.1404. In thrombolytic activity using in vitro clot lysis assay method, the ethyl acetate soluble fraction (LEAF) and n-hexane soluble fraction(LHXF) of leaf extract was found to have significant (p<0.001), thrombolytic activity showed a maximum effect of 44.293±0.5069 & 44.211±0.7428 while the standard streptokinase showed 71.668±0.466.
Language: English
Citation: Mohammed, A. S., Faruk, Md., Chowdhury, A. I., Faisal, A. R., Al Mamun, A., et al. (2014) Thrombolytic and anti-arthritic activities of methanolic extract of trevesia palmata. "e-Journal of Science & Technology". [Online] 9(5). p. 119-124. Available from: [Accessed 17-02-2015]
Journal: e-Περιοδικό Επιστήμης & Τεχνολογίας
e-Journal of Science & Technology
Type of Journal: With a review process (peer review)
Access scheme: Publicly accessible
License: Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες
Appears in Collections:Τόμος 09, τεύχος 5 (2014)

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